Wednesday, June 17, 2020

CELL ORGANELLES - NUCLEUS

NUCLEUS

  • first described by Robert Brown.
  • Nucleus was named chromatin by Flemming.

  • The interphase ( non dividing cell phase) nucleus has highly extended and elaborate nucleoprotein fibres called chromatinnuclear matrix and one or more spherical bodies called nucleoli.
  • The nuclear envelope consists of two parallel membranes with a space between them called the perinuclear space.
  • At a number of places, the nuclear envelope is interrupted by minute pores, which are formed by the fusion of its two membranes.
  • nuclear matrix --nucleoplasm
  • The nucleoli are spherical structures present in the nucleoplasm.
  • Nucleolus is the site of active ribosomal RNA (rRNA) synthesis.

  • A loose and indistinct network of nucleoprotein fibres is called chromatin.
  • During different stages of cell division, cells show structured chromosomes in place of the nucleus.
  • Chromatin contains DNA and some basic proteins called histones, some non-histone proteins and also RNA.

  • Every chromosome -- a primary constriction or the centromere on the sides of which disc shaped structures called kinetochore are present.

  • Based on the position of the centromere, the chromosomes can be classified into four types
  • Metacentric
  • Submetacentric
  • Acrocentric
  • Telocentric

  • The metacentric chromosome has middle centromere -- two equal arms of the chromosome.
  • The sub-metacentric chromosome has centromere nearer to one end of the chromosome -- one shorter arm and one longer arm.
  • In case of acrocentric chromosome, the centromere is situated close to its end -- one extremely short and one very long arm
  •  telocentric chromosome -- terminal centromere.

  • Sometimes a few chromosomes have non-staining secondary constrictions, which gives the appearance of a small fragment called the satellite - SAT CHROMOSOME.

MICROBODIES

  • Many membrane bound minute vesicles are called microbodies.
  • Microbodies contain various enzymes, are present in both plant and animal cells.

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